Man Utd v Southampton line-ups: Mourinho makes several changes, Mata starts

The 28-year-old has been in his homeland since Thursday after the death of his grandfather.

But Mata takes his place alongside Jesse Lingard and Anthony Martial in the attacking three behind Zlatan Ibrahimovic.

Michael Carrick is only fit enough to start from the bench after coming off with a knock against St Etienne on Wednesday.

Captain Wayne Rooney is also named as a substitute.

Man Utd: De Gea, Valencia, Bailly, Smalling, Rojo, Herrera, Pogba, Mata, Lingard, Martial, Ibrahimovic

Subs: Romero, Blind, Young Fellaini, Carrick, Rooney, Rashford

Southampton: Forster; Cédric, Yoshida, Stephens, Bertrand; Romeu, Davis, Ward-Prowse, Tadić; Redmond, Gabbiadini

Subs: Hassen, Long, Rodriguez, Caceres, Boufal, Hojbjerg, McQueen.